Estrogen-induced regression of coronary atherosclerosis in cholesterol-fed chicks.
نویسندگان
چکیده
The present study demonstrates that estrogens reverse previously induced coronary atherosclerosis in cholesterol-fed cockerels, despite the continued presence of the atherogenic stimulus in the diet. Aorta atherogenesis remains unaffected. Hypercholesterolemia is moderately enhanced by estrogen administration; total cholesterol-lipid phosphorus (C/P) ratios are depressed to normal levels, consequent upon estrogen-induced hyperphospholipemia.
منابع مشابه
Effects of testosterone and castration on cholesteremia and atherogenesis in chicks on high fat, high cholesterol diets.
IT IS a well documented fact that a significant sex differential exists in severity of coronary atherosclerosis and incidence of coronary heart disease in middle-aged human beings." Considerable evidence is available to indicate that ovarian estrogen secretion is a key factor in protection of premenopansal women from this disease. ~ Little evidence is available concerning the relationship of an...
متن کاملEffects of Testosterone and Castration on Cholesteremia and Atherogenesis in Chicks on High Fat, High Cholesterol Diets
IT IS a well documented fact that a significant sex differential exists in severity of coronary atherosclerosis and incidence of coronary heart disease in middle-aged human beings." Considerable evidence is available to indicate that ovarian estrogen secretion is a key factor in protection of premenopansal women from this disease. ~ Little evidence is available concerning the relationship of an...
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Until recently it was believed that atherosclerotic lesions of the aorta induced by hypercholesterolemia always faithfully reflected changes in other arteries. Thus intensive experimental analysis of factors reducing hypercholesterolemia and protecting the aorta against atherosclerosis were undertaken in the belief that such factors would also protect the coronary and other arteries against ath...
متن کاملEffects of Hypothyroidism on Estrogen-Induced Inhibition of Coronary Atherogenesis in Cholesterol-Fed Cockerels
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متن کاملMorphopathological study of effect of Licorice root extract on atherosclerosis process in coronary artery of male fed rabbit
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ورودعنوان ژورنال:
- Circulation
دوره 6 6 شماره
صفحات -
تاریخ انتشار 1952